Monte-Carlo dosimetry on a realistic cell monolayer geometry exposed to alpha particles

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Monte-Carlo dosimetry on a realistic cell monolayer geometry exposed to alpha particles.

The energy and specific energy absorbed in the main cell compartments (nucleus and cytoplasm) in typical radiobiology experiments are usually estimated by calculations as they are not accessible for a direct measurement. In most of the work, the cell geometry is modelled using the combination of simple mathematical volumes. We propose a method based on high resolution confocal imaging and ion b...

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ژورنال

عنوان ژورنال: Physics in Medicine and Biology

سال: 2012

ISSN: 0031-9155,1361-6560

DOI: 10.1088/0031-9155/57/8/2189